Eptifibatide mo te maimoatanga o te mate kino kino 188627-80-7
Taipitopito Hua
| Ingoa | Eptifibatide |
| nama CAS | 188627-80-7 |
| tātai rāpoi ngota | C35H49N11O9S2 |
| Te taumaha ngota | 831.96 |
| Tau EINECS | 641-366-7 |
| Kiato | 1.60±0.1 g/cm3(Te Matapae) |
| Nga tikanga rokiroki | Kua hiri ki te maroke, rongoa ki roto i te pouaka tio, i raro i te -15°C |
Nga kupu taurite
Eptifibatideacetatesalt;Eptifibatide,MPA-HAR-Gly-Asp-Trp-Pro-Cys-NH2,MPAHARGDWPC-NH2,>99%;MAP-LYS-GLY-ASP-TRP-PRO-CYS-NH2;INTEGRELIN;Eptifibatide;N6-(Aminoimi nomethyl)-N2-(3-mercapto-1-oxopropyl-L-lysylglycyl-La-aspartyl-L-tryptophyl-L-prolyl-L-cysteinamide;MPA-HAR-GLY-ASP-TRP-PRO-CYS-NH2(DISULFIDEBRIDGE,MPA1-CYS6).
Te Kaiwhangai Antagonist Glycoprotein Platelet
Ko te Etifibatide (integrilin) he puiao polypeptide platelet glycoprotein IIb/IIIa receptor antagonist, e aukati ana i te whakahiato pereti me te thrombosis ma te aukati i te huarahi whakamutunga o te whakahiato pereti. Ki te whakatauritea ki te monoclonal antibody abciximab, he kaha ake te kaha o te eptifibatide, he tino aronga me te herenga motuhake ki te GPIIb/IIIa na te mea he kotahi te whakakapinga waikawa amino-a-lysine hei whakakapi i te arginine. Na reira, kia whai i te reira i te pānga haumanu pai i roto i te maimoatanga wawaotanga o te syndrome coronary whakapeka. He maha nga wa i whakawhanakehia ai nga raau taero antagonist antagonist platelet glycoprotein IIb/IIIa, a i tenei wa e 3 nga momo whakaritenga ka taea te whakamahi i roto i te haumanu o te ao, abciximab, eptifibatide me te tirofiban. ). He iti noa nga wheako ki te whakamahi i nga kaitao kaikawe GPIIb/IIIa pereti glycoprotein i Haina, a he iti rawa nga raau taero e waatea ana. Kotahi noa te rongoa, ko te tirofiban hydrochloride, kei te maakete. Na reira, i hangaia he pereti glycoprotein IIb hou. /IIIa he mea nui nga kaitukino kaiawhina. Ko te eptifibatide o te kainga he hua tauira na Chengdu Sino Biological Products Co., Ltd.
whakarōpūtanga
Te whakarōpūtanga o nga raau taero Antiplatelet Aggregation
Ka taea te wehewehea nga raau taero whakahiato antiplatelet ki nga waahanga e toru: 1. Nga aukati Cyclooxygenase-1 (COX-1), penei i te aspirini. 2. Aukati i te whakahiato platelet i whakaawehia e te adenosine diphosphate (ADP), penei i te clopidogrel, te prasugrel, te cangrelor, te ticagrelor, me etahi atu. nga waahanga matū me nga tangohanga whai hua mai i nga rongoa Hainamana tuku iho.
