Palopegteriparatide

Palopegteriparatide API

Ko te Palopegteriparatide he agonist-agonist-a-parathyroid hormone receptor agonist (PTH1R agonist), i hangaia mo te maimoatanga o te hypoparathyroidism tawhito. He tairitenga pegylated o PTH (1-34) i hangaia hei whakarato i te ture konupūmā mau tonu me te horopeta kotahi-wiki.

Hangahanga me te Rangahau:
Ka herea te Palopegteriparatide ki nga kaiwhakawhiwhi PTH1, ka whakahoki i te toenga konupora me te phosphate ma te:

• Te whakanui ake i te konupūmā serum

• Te whakaheke i te tango konupūmā mimi

• Te tautokote pākia wheua me te kohuke homeostasis