Hua
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CJC-1295
Ko te CJC-1295 API ka hangaia ma te whakamahi i te hangarau peptide synthesis (SPPS) waahanga totoka me te purea ma te whakamahi i te HPLC hei whakatutuki i te parakore teitei me te riterite o te puranga-ki-te-puranga.
Āhuatanga Hua:Pure ≥ 99%
He iti te toenga whakarewa me nga konganuku taumaha
Ko te ara whakahiato kore-immunogenic kore-endotoxin
Te rahinga whakarite: mg ki kg
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NAD+
Āhuatanga API:
Te parakore teitei ≥99%
NAD+ mokamoka rongoa
Nga paerewa hangahanga rite-GMP
Ko te NAD+ API he pai mo te whakamahi i roto i nga rongoa rongoa, injectables, me nga rongoatanga metabolic matatau.
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Boc-Tyr(tBu)-Aib-Glu(OtBu)-Gly-OH
Boc-Tyr(tBu)-Aib-Glu(OtBu)-Gly-OHhe tetrapeptide parea e whakamahia ana i roto i te rangahau whakahiato peptide. Ko nga roopu Boc (tert-butyloxycarbonyl) me te tBu (tert-butyl) he roopu whakamarumaru hei aukati i nga tauhohenga taha i te wa o te huihuinga mekameka peptide. Ko te whakauru o te Aib (a-aminoisobutyric acid) ka awhina i nga hanganga helical me te whakanui ake i te pumau o te peptide. Ko tenei raupapa peptide e akohia ana mo tona kaha ki te wetewete ritenga, te whakakopa i te peptide, me te hei poraka whare ki te whakawhanake i nga peptides koiora me te pai ake o te pumau me te motuhake.
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Cagrilintide
Ko te Cagrilintide he hangai, he roa te mahi agonist whakawhiwhi amylin i hangaia mo te maimoatanga o te momona me nga mate mate e pa ana ki te taumaha. Ma te peehi i te amylin homoni taiao, ka awhina i te whakarite i te hiahia, te puhoi o te kopu, me te whakanui i te makona. Ko ta tatou API Cagrilintide tino parakore ka hangaia ma te whakahiato matū me te tutuki i nga paerewa reanga rongoa, e pai ana mo te whakamahi i roto i nga whakatakotoranga whakahaere taumaha.
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Tesamorelin
Kei te whakamahi a Tesamorelin API i te hangarau peptide synthesis o te wahanga totoka (SPPS) me nga ahuatanga e whai ake nei:
Pure ≥99% (HPLC)
Kaore he endotoxin, he konganuku taumaha, he toenga whakarewa i whakamatauria
Ko te raupapa waikawa amino me te hanganga i whakapumautia e LC-MS / NMR
Whakaratohia te hanga i roto i te karamu ki te kirokaramu -
Fmoc-Ile-Aib-OH
Ko te Fmoc-Ile-Aib-OH he poraka hanga dipeptide e whakamahia ana i roto i te whakahiato peptide-waahanga (SPPS). Ka honohia e ia te isoleucine e tiakina ana e Fmoc me te Aib (a-aminoisobutyric acid), he waikawa amino kore-taiao e whakarei ake ana i te pumau o te helix me te aukati protease.
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![Fmoc-L-Lys[Eic(OtBu)-γ-Glu(OtBu)-AEEA-AEEA]-OH](https://cdn.globalso.com/gentolexgroup/Glepaglutide6-300x300.png)
Fmoc-L-Lys[Eic(OtBu)-γ-Glu(OtBu)-AEEA-AEEA]-OH
Ko te Fmoc-L-Lys[Eic(OtBu)-γ-Glu(OtBu)-AEEA-AEEA]-OH he paraka hanga waikawa amino i hangaia mo te tuku tarukino me te bioconjugation. Kei roto i te waahanga Eic (eicosanoid) mo te taunekeneke lipid, γ-Glu mo te whaainga, me nga mokowhiti AEEA mo te ngawari.
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Boc-Tyr(tBu)-Aib-OH
Ko te Boc-Tyr(tBu)-Aib-OH he poraka hangahanga dipeptide whakamarumaru e whakamahia ana i roto i te whakahiato peptide, te whakakotahi i te tyrosine kua tiakina e Boc me te Aib (a-aminoisobutyric acid). Ko te toenga o te Aib ka whakarei ake i te hanga helix me te aukati protease.
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Boc-Tana(Trt)-Ala-Glu(OtBu)-Gly-OH
Ko Boc-His(Trt)-Ala-Glu(OtBu)-Gly-OH he kongakonga tetrapeptide parea e whakamahia ana i roto i te whakahiato peptide-waahanga totoka (SPPS) me te whanaketanga tarukino peptide. Kei roto ko nga roopu whakamarumaru mo te whakahiato orthogonal me te whakaatu i tetahi raupapa whai hua ki te hoahoa peptide koiora me te hanganga.
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Fmoc-Lys(Pal-Glu-OtBu)-OH
Ko te Fmoc-Lys(Pal-Glu-OtBu)-OH he poraka hangahanga waikawa amino lipidated motuhake i hangaia mo te whakakotahitanga peptide-lipid. Kei roto i te lysine e tiakina ana e Fmoc me te mekameka taha palmitoyl-glutamate, te whakarei ake i te hononga membrane me te koiora.
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Fmoc-His-Aib-OH
Ko te Fmoc-His-Aib-OH he poraka hangahanga dipeptide e whakamahia ana i roto i te whakahiato peptide, te whakakotahi i te histidine kua tiakina e Fmoc me te Aib (a-aminoisobutyric acid). Ka whakaatu a Aib i te rigidity conformational, he mea nui mo te hoahoa peptides helical me te pumau.
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Boc-Tana(Trt)-Aib-Glu(OtBu)-Gly-OH
Ko te Boc-His(Trt)-Aib-Glu(OtBu)-Gly-OH he kongakonga tetrapeptide kua tiakina e whakamahia ana i roto i te whakahiato peptide me te whanaketanga tarukino. Kei roto i nga roopu mahi kua parea rautaki mo te hono takahanga me te whakaatu i te Aib (a-aminoisobutyric acid) hei whakarei ake i te pumau o te helix me te rigidity conformational.