Ko te RU-58841 i whakamahia hei aukati i nga makawe me te pakira tauira tane
Taipitopito Hua
| Ingoa | RU-58841 |
| nama CAS | 154992-24-2 |
| tātai rāpoi ngota | C17H18F3N3O3 |
| Te taumaha ngota | 369.34 |
| Tau EINECS | 1592732-453-0 |
| Kohuatanga | 493.6±55.0 °C(Te Matapae) |
| Kiato | 1.39 |
| Te ahua rokiroki | Kua hiri ki te maroke, Rokiroki i roto i te pouaka tio, i raro i te -20°C |
| Puka | Paura |
| Tae | Mā |
| Te takai | Peeke PE + putea Aluminium |
Nga kupu taurite
RU58841;4-(4,4-Dimethyl-2,5-dioxo-3-(4-hydroxybutyl)1-imidazolidinyl)-2-(trifluoromethyl)benzonitrile;4-[3-(4-Hydroxybutyl)-4,4-dimethyl-2,5-dioxo-1-imidazolidinyl(nylimazolidi)-methyl. onitrile;4-[3-(4-Hydroxybutyl)-4,4-diMethyl-2,5-dioxoiMidazolidin-1-yl]-2-(trifluoroMethyl)ben zonitrile;RU-58841E:candyli(at)speedgainpharma(dot)com;CS-637;RU588841;RU58841;RU58841;RU-58841
Pānga Rongoā
Whakaahuatanga
Ko te RU 58841 (PSK-3841) he kaitoi antagonist receptor androgen e whakatairanga ana i te tipu o nga makawe.Ko te RU58841 he rongoa whakatewhatewha i hangaia hei rongoa mo te alopecia androgenic, e mohiotia ana ko te pakira tane (MPD).
I te mea he kaupapa anti-androgen, ko tana kaupapa mahi kaore i te rite ki te finasteride. Ka mahi tika a Finasteride ki te 5α reductase, ka aukati i te huringa o te testosterone ki te DHT, me te whakaheke i te ihirangi o te DHT i roto i te tinana. RU58841 poraka te whakapā i waenganui i dihydrotestosterone me te makawe follicle receptors, e kore e tika whakaiti DHT ihirangi, engari whakaiti reira te here o DHT me te makawe follicle receptors, kia rite ki te whakatutuki i te kaupapa o te maimoatanga alopecia androgenetic.
4-[3-(4-Hydroxybutyl)-4,4-dimethyl-2,5-dioxo-1-imidazolidinyl]-2-(trifluoromethyl)benzonitrile Ka taea te whakamahi hei rongoa Nga takawaenga matū matū.Mena ka ngohia te 4-[3-(4-hydroxybutyl)-4,4-dimethyl-2,5-dioxo-1-imidazolidinyl]-2-(trifluoromethyl)benzonitrile, Nekehia te manawanui ki te hau hou;Mena ka pa ki te kiri, tangohia nga kakahu kua poke, horoia te kiri ki te hopi me te wai, me te rapu rongoa mena ka pa te mamae;
Pānga taha
Ka whakamahia te RU58841 ki te mahunga, ka mauhia e nga makawe makawe, me te whakaaro, ka uru ki roto i te toto ka pa ki etahi atu waahanga o te tinana. Engari kaore i kitea nga paanga taha punaha i roto i nga rangahau mo te tono kaupapa i roto i nga makimaki. Engari, ko etahi o nga tangata kua whakamatau i te RU58841 e kii ana kua pa ki a ratou etahi paanga o te taha mai i te whakamahi i te RU, tae atu ki te mamae o te kiri, te heke o te libido, te mate erectile, te nausea, te whero nga kanohi, te whanoke, me te mahunga.
