Ingoa | Sildenafil currate |
Ka taea te nama | 171599-83-0 |
He tātai konukawata | C28h38n6o11s |
Taumaha Momo | 666.70 |
Te tau einecs | 200-659-6 |
Mema | 14,8489 |
Tōnu | 1.445g / cm3 |
Te tikanga rokiroki | 2-8 ° C |
Āhua | Paura |
Tae | Mā |
Te whakaheke wai | DMSO:> 20MG / ML |
Viagra, sildenafil currate; 1 - [3- (4,7-dihydro-1-atyll-7-pyrazolo [4,3-d] pyrimidin-5-yl) -4-ethoxypheny] 5- [2-ethoxy-5- (4-methylpiperazin-1-yl) sulfonylphenyl] -1-atyll-3-pyrazolo [5,4-e] Pyrimidin-7-Onecitrates; 1 - [3- (6,7-dihydro-1-atyll-7-pyrazolo [4,3-atyoxyphenyl] Sildenafilcrate (100mg); Sildenafilciterate,> = 99%; Sildenafilcitete, ngaiotanga; 5- [2-ethoxy-5 - (4-methyl-piperazin-1-yl) sulnyl] -1,6-dihydrol-1-pyrazolo [4,3-d] Pyrimidin-7-Oracite
Te mahi rongoā rongoā
Ko SildenAfil Citrate he 5-phosphodiesseralruaralruaral te whakarei ake i te onlic exine monophosphate me te aukati i te pakaru o te huringa o te huringa o te huringa guanoine monoposphate. I tua atu i te whakawhanaketanga tika o nga oko toto puuturu, ka taea hoki te aukati, te hurihuri ano hoki.
Nga rongoa me nga tono
Ko SildenAfil Curtent, ingoa hokohoko na te mea i mohiotia ai ko Viagrahosphate (CGMP Guanonine Monophosphate (CGMPific ChosphosAs Whakahoahoa ka taea te whakarei ake i nga mahi a te Tari Whakahaere. Ka taea e SildenAfil Citrate te whakarei ake i te hua o te Nitric Oxide (kaore) ma te aukati i te Momo 5 phosphodiesterase i te ceclosine guanosine monophosphate. Whakanuia te taumata o te CGMP i roto i te Corpus Cavernosum, okioki te uaua maeneene i roto i te Corpus Cavernosum, whakapiki i te toto toto, te roa o te wa whakatikatika. Mo te poke i nga turoro me te kore erectile. Ko nga pakeke e 50 mg i ia wa, tae atu ki te 1 wa ia ra, me te whakamahi i te 1 haora i mua i te moepuku. Ko te moni nui ko te 0.1g ia wa.
I nga rangahau vivo
I roto i nga kuri whaihua, ko Sildenafil citrate e whakarei ake i te mahi eretile penile i raro i te whakaongaonga nerve nervic ma te ine i te pehanga intracavernous. Ko SildenAfil Curter te whakarereke i te whakangahau i te carbamoylcholine-whakaongaonga me te aukati i te hanganga superyoxide i te kiko onosal o nga rapeti hyperchesteryolemic. I roto i te reanga sprague-dawley, ka pai ake a Sildenafil i roto i te waa e whakawhirinaki ana ki te waa-distecce, me te whakaoranga whakanui i te ra 28 mg / kg ia ra. I roto i nga kiore Sprague-Dawley, te whakahaere a Sildenafil i hua mai i te tiakitanga uaua o te Clascle Collage me te whakaaturanga CD31 me te enos whakapuaki. I roto i te repts sprague-dawley, i tino whakahekehia e Sildenafil te tohu apoptotic ka piki ake te phosphory of Akt me Enos i whakaritea ki te roopu whakahaere.