Tirzepatide Lyophilized High Purity 99% Peptide Powder 60mg mo ia ipu mo te mate huka me te mate taimaha
Taipitopito Hua
| Ingoa | Tirzepatide Werohanga Paura |
| Maamaa | 99% |
| Te ahua | Paura Lyophilized White |
| Whakahaerenga | Werohanga Subcutaneous |
| Rahi | 10mg, 15mg, 20mg, 30mg, 60mg |
| Wai | 3.0% |
| Nga painga | Te rongoa i te mate huka, te mate taimaha |
Whakaahuatanga
Tirzepatide Lyophilized Paura (60 mg)
Ko Tirzepatide (LY3298176) te agonist mahi-rua tuatahi e aro ana ki nga kaiwhakawhiwhi GIP (te insulinotropic polypeptide e whakawhirinaki ana ki te huka) me te GLP-1 (glucagon-like peptide-1). I whiwhi whakaaetanga a te US FDA i Mei 2022 mo te maimoatanga o te mate huka mellitus momo 2 (T2DM) hei taapiri mo te kai me te korikori tinana.
Ka tukuna tenei hua hei 60mg lyophilised (maroke-maroke) paura horomata i roto i nga ipu, me whakahou ki te wai bacteriostatic i mua i te whakahaere. Ka whakatauritea ki nga agonists kaikawe GLP-1 kotahi penei i te semaglutide, dulaglutide ranei, ka whakaatu te tirzepatide i te kaha ki te whakapai ake i te ture huka toto, te whakarei ake i te taikaha o te insulin, me te tautoko i te mate taumaha. Ko enei painga e pa ana ki tana tikanga mahi tahi-rua.
Nga Painga Matua
Te Mana Glycemic
- Ka whakaihiihi i te hunanga o te insulin i runga i nga tikanga e whakawhirinaki ana ki te huka
- He whakaheke i te hunanga o te glucagon, he pai te whakaheke i nga taumata huka toto
- Ka whakatauira i te whakakotahitanga o nga paanga o te GIP me te GLP-1
Whakahaere Taumaha
- Ka whakatairanga i te makona me te whakaiti i te horomanga caloric
- I whakaatu i te nui me te mau tonu o te mate taimaha i roto i nga rangahau haumanu
Hauora Cardiovascular
- Ko nga raraunga tuatahi e tohu ana ka taea te whakaiti i te tupono o te mate cardiovascular i nga turoro me te T2DM
Te Whakamahi me te Inenga
- Tirzepatide lyophilized paura (60 mg) me hanga ki te wai bacteriostatic i mua i te whakamahi. Ko te whakahaere ma te werohanga i raro i te kiri, ko te tikanga kotahi ia wiki i te ra kotahi i ia wiki.
Momo mate huka 2
- Tohenga Timata: 2.5 mg kotahi wiki
- Titration: Whakanuia ia 4 wiki kia rite ki te whakaae
- (→ 5 mg → 7.5 mg → 10 mg → 12.5 mg → 15 mg → 20 mg → 30 mg → 45 mg → ki te 60 mg)
- Te horopeta noa: 10–30 mg ia wiki
- Inenga Morahi: 60 mg ia wiki
Te Momomoana / Whakahaere Taumaha
- Tohenga Timata: 2.5 mg kotahi wiki
- Titration: Te piki haere o te horopeta ka whakaaetia
- (2.5 → 5 → 7.5 → 10 → 12.5 → 15 → 20 → 30 → 45 → 60 mg)
- Te horopeta noa: 30–60 mg ia wiki
- Inenga Morahi: 60 mg ia wiki
Whakatauritenga Inenga Manako
| Tohutohu | Te Inenga Timata | Apiti Titration | Inenga noa | Inenga Morahi | Auautanga |
|---|---|---|---|---|---|
| Momo mate huka 2 | 2.5 mg ia wiki | Whakanuia ia 4 wiki (→ 5 → 7.5 → 10 → 12.5 → 15 → 20 → 30 → 45 → 60) | 10–30 mg ia wiki | 60 mg ia wiki | Kia kotahi wiki |
| Te Momona / Ngaronga Taumaha | 2.5 mg ia wiki | Whakanuia i runga i te manawanui (2.5 → 5 → 7.5 → 10 → 12.5 → 15 → 20 → 30 → 45 → 60) | 30–60 mg ia wiki | 60 mg ia wiki | Kia kotahi wiki |
Tuhipoka:Me whakarite kia pai te aro o ia horopeta o mua i mua i te pikinga.
Nga Tauhohenga Kino pea
- Gastrointestinal: Nausea, ruaki, korere, me te mamae o te puku (te nuinga i te wa e timata ana)
- Hypoglycemia: I te nuinga o te waa he iti te tupono, engari ka piki ake ina honoa ki etahi atu rongoa rongoa mate huka
- Nga Tauhohenga o te Pae Werohanga: Te whero, te patito, te pupuhi, te mamae ngawari ranei i te waahi
- Pancreatitis: He onge engari ka taea; aroturuki mo te mamae tonu o te puku
- Nga Painga Renal: Ka hiahiatia pea te aro turuki i nga mahi o te whatukuhu i etahi tangata
Pharmacokinetics
- Hawhe-ora: Tata ki te 1 wiki
- Auautanga Tota: Ka tautoko i te watea i te whakahaerenga kotahi-wiki
Whakarāpopototanga
Ko te Tirzepatide 60 mg te paura lyophilized e tohu ana i te ahunga whakamua rongoa o muri mai, me te whakakotahi i te mana glycemic kaha me te kaha o te mate taumaha me te tiaki mate cardiovascular.
Ma te raupapa titration āta (2.5 mg → ki te 60 mg), ka taea e ia te whakapai ake i te manawanui me te ngawari mo te maimoatanga takitahi. Ko tana whakahaerenga kotahi-wiki ka pai ake te piri, ka waiho hei whiringa hou me te whai hua mo te whakahaere i te mate huka momo 2 me te momona i roto i nga waahi haumanu me nga waahi rangahau.
