Ko te Vancomycin he paturopi glycopeptide e whakamahia ana mo te paturopi
Taipitopito Hua
| Ingoa | Vancomycin |
| nama CAS | 1404-90-6 |
| tātai rāpoi ngota | C66H75Cl2N9O24 |
| Te taumaha ngota | 1449.25 |
| Tau EINECS | 215-772-6 |
| Kiato | 1.2882 (whakatau tata) |
| Taupū Refactive | 1.7350 (whakatau tata) |
| Nga tikanga rokiroki | Kua hiri ki te maroke, 2-8°C |
Nga kupu taurite
Vancomycin(baseand/orunspecifiedsalts);VANCOMYCIN;VancomycinBase;(3S,6R,7R,22R,23S,26S,36R,38aR)-3-(2-Amino-2-oxoethyl)-44-[[2-O-,3-amino-2 3,6-trideoxy-3-C-methyl-α-L-lyxo-hexopyranosyl)-β-D-glucopyranosyl]oxy]-10,19-dichloro-2,3,4,5,6,7,23,24,25,26,36,37,38,38a-7tetradecahydro ,22,28,30,32-pentahydroxy-6-[[(2R)-4-methChemicalbookyl-2-(methylamino)-1-oxopentyl]amino]-2,5,24,38,39-pentaoxo-22H-8,11:18,21-Dietheno-23, 36-(iminomethano)-13,16:31,35-dimetheno-1H,16H-[1,6,9]oxadiazacyclohexadecino[4,5-m][10,2,16]benzoxadiazacyclotetracosine-26-carboxylicacid.
Whakaahuatanga
Ko te Vancomycin he antibiotic glycopeptide. Ko tana tikanga o te mahi ko te here me te tino hononga ki te alanylalanine i te mutunga o te poly-terminal o te peptide precursor o te pakitara huakita kirikiri tairongo, te aukati i te whakahiato o te peptidoglycan macromolecular e hanga ana i te pakitara o te pūtau huakita, ka puta ko te whakangaromanga o te pakitara pūtau ka mate huakita. He whai hua te Vancomycin mo nga mate kino na te huakita Gram-positive, ina koa na te methicillin-resistant Staphylococcus aureus, Staphylococcus epidermidis, me Enterococcus e atete ana ki etahi atu paturopi, he ngoikore ranei te kaha.
Tohutohu
He iti noa ki nga mate nahanaha na te Staphylococcus aureus (MRSA) me te methicillin-resistant Staphylococcus aureus (MRSA) me nga mate whekau me nga mate punaha na te Clostridium difficile; Kare e taea e nga turoro mate-mate ki te whakamahi penicillins, cephalosporins ranei i roto i nga turoro he mate staphylococcal nui, te hunga ranei he mate staphylococcal nui kaore i aro ki nga paturopi o runga ake nei, ka taea te whakamahi i te vancomycin. Ka whakamahia ano tenei hua mo te maimoatanga o te Enterococcus endocarditis me te Corynebacterium (Diphtheria-like) endocarditis i roto i nga tangata e mate ana ki te penicillin. Te maimoatanga o nga mate shunt arteriovenous na te staphylococcus i roto i nga turoro hemodialysis e mate mate ana ki te penicillin me te kore mate ki te penicillin.
![Fmoc-L-Lys[Ste(OtBu)-γ-Glu-(OtBu)-AEEA-AEEA]-OH](https://cdn.globalso.com/gentolexgroup/Glepaglutide9-300x300.png)