Cagrilintide

Whakaahuatanga Poto:

Ko te Cagrilintide he hangai, he roa te mahi agonist whakawhiwhi amylin i hangaia mo te maimoatanga o te momona me nga mate mate e pa ana ki te taumaha. Ma te peehi i te amylin homoni taiao, ka awhina i te whakarite i te hiahia, te puhoi o te kopu, me te whakanui i te makona. Ko ta tatou API Cagrilintide tino parakore ka hangaia ma te whakahiato matū me te tutuki i nga paerewa reanga rongoa, e pai ana mo te whakamahi i roto i nga whakatakotoranga whakahaere taumaha.

Tukuna he imeera ki a matou

Taipitopito Hua

Tohu Hua

Cagrilintide API

Cagrilintidehe mahi roa, kua whakahiatotia matūte agonist kaiawhina amylin, i whakawhanakehia hei maimoatanga hou momōmona me te mate pākia e pā ana ki te taumaha. Kua hoahoatia hei whakatauira i nga paanga oamylin tangata, he homoni i huna tahi me te insulin e nga pūtau β-pancreatic, he mahi nui ki te whakahaere i te kai, te putunga puku, me te makona.

Kei te whakawhanakehia te Cagrilintide hei akotahi-wiki te rongoa injectable, tuku he otinga tino pai mote whakahaere taimaha roa, ina koa ka whakamahia i rotote whakakotahitanga me nga agonists kaiawhina GLP-1peneiSemaglutide.

Hangahanga Mahi

Ka whakamahia e te Cagrilintide ona hua rongoa ma te here me te whakahohenga kaiwhakawhiwhi amylin, ka arahi ki:

Te whakakore i te hiahia
Kua roa te putunga o te kopu, e whakaroa ana i te ahua o te ki tonu
Kua whakaitihia te kai o te kaarai me te whakanui ake i te makona

Ko tenei ture maha mo te kai kai ka waiho hei kaitono pai mo te whakahaeremōmona me ngā mōrea cardiometabolic pātahi.

Rangahau me nga Raraunga Haumanu

Kua whakaatuhia e Cagrilintide nga hua pai i roto i te maha o nga whakamatautau haumanu, tae atu kiWāhanga 2 rangahau i whakahaerehia e Novo Nordisk:

Ina whakamahiaanake, Cagrilintide arata'i kimate taimaha e whakawhirinaki ana ki te horopeta, tae noa ki10.8% te whakaheke taimaha tinananeke atu i te 26 wiki ki te hunga momomomo.
Inakua honoa ki a Semaglutide, ka tino whakanuia te paanga o te mate taimaha—te whakatutukihe nui ake te whakahekenga o te taumaha o te tinana i te kaihoko anake.
Kua whakaatute pai o te manawanuiahe pūkete haumaru pūmau, me te nuinga o nga mea kino he tohu ngawari o te gastrointestinal.

Ko tenei huarahi whakakotahi he waahanga nui o tepaipa tarukino anti-momona whakatupuranga muri, e aro ana ki nga ara makona maha (amylin + GLP-1).

Kounga API me te Hangahanga

To tatouCagrilintide API:

Ka whakaputahia ma te matataute whakahiato peptide-waa toka (SPPS)me te tino parakore me te pumau matū
Kua hoahoa mowhanaketanga hanga injectable
Ka tutaki ki te aonga paerewa rongoa (ICH, GMP, FDA)
Kei te waatea i rotote kaiurungi ki te hanga tauine arumoni, he pai mo te mahi haumanu me te ahumahi