Pegcetacoplan

API Pegcetacoplan

Ko te Pegcetacoplan he pegylated cyclic peptide e mahi ana hei aukati awhina C3 kua whakaritea, i whakawhanakehia mo te maimoatanga o nga mate whakauru-whakawhitiwhiti penei i te paroxysmal nocturnal hemoglobinuria (PNH) me te atrophy matawhenua (GA) i roto i te paheketanga macular e pa ana ki te tau.

Hangahanga me te Rangahau:
Ka herea a Pegcetacoplan ki te whakakii i te pūmua C3 me te C3b, hei aukati i te whakahohenga o te cascade. Ka whakaiti tenei:
Hemolysis me te mumura i roto i te PNH
Te kino o nga pūtau retina i te atrophy matawhenua
Ko te whara o te kopa arai i roto i etahi atu mate e pa ana ki te awhina