Atosiban Acetate Used for Anti Premature Birth Featured Image

Ko te Atosiban Acetate e whakamahia ana mo te whanautanga o mua

Whakaahuatanga Poto:

Ingoa: Atosiban

Nama CAS: 90779-69-4

tātai rāpoi: C43H67N11O12S2

Te taumaha ngota: 994.19

Tau EINECS: 806-815-5

Wāhi koropupū: 1469.0±65.0 °C (Te Matapae)

Kiato: 1.254±0.06 g/cm3(Whakaahua)

Nga tikanga rokiroki: -20°C

Wairewa: H2O: ≤100 mg/mL

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Taipitopito Hua

Tohu Hua

Taipitopito Hua

Ingoa	Atosiban
nama CAS	90779-69-4
tātai rāpoi ngota	C43H67N11O12S2
Te taumaha ngota	994.19
Tau EINECS	806-815-5
Kohuatanga	1469.0±65.0 °C (Te Matapae)
Kiato	1.254±0.06 g/cm3(I Matapaetia)
Nga tikanga rokiroki	-20°C
Wairewa	H2O: ≤100 mg/mL

Whakaahuatanga

Ko te Atosiban acetate he polypeptide cyclic here-disulfide e 9 nga waikawa amino.He ngota ngota oxytocin kua whakarereketia i nga waahi 1, 2, 4 me 8. Ko te N-terminus o te peptide he waikawa 3-mercaptopropionic (thiol me Ko te roopu sulfhydryl o [Cys]6 ka hanga he here disulfide), ko te C-terminal he i roto i te ahua o te amide, ko te waikawa amino tuarua kei te N-terminal he ethylated [D-Tyr(Et)]2, ka whakamahia te acetate atosiban i roto i nga rongoa hei winika Kei te ahua o te tote waikawa, te nuinga. e mohiotia ana ko te atosiban acetate.

Taupānga

Ko te Atosiban he oxytocin me te vasopressin V1A he kaiwhakawhanake kaiawhina whakahiato, he rite tonu te hanganga o te kaiawhina oxytocin ki te kaitoha vasopressin V1A.I te wa e aukatihia ana te kaitoi oxytocin, ka taea tonu e te oxytocin te mahi na roto i te kaiwhakawhiwhi V1A, na he mea tika ki te aukati i nga huarahi e rua o runga ake nei i te wa kotahi, a, ka taea e te antagonism kotahi o tetahi kaiwhiwhi te whakakore i te whakawhitinga o te kopu.Koinei hoki tetahi o nga tino take e kore ai e taea e te hunga agonists β-receptor, te aukati hongere konupūmā me te aukati synthase prostaglandin te aukati i te whakahekenga o te uterine.

Pānga

Ko te Atosiban he kaiwhakawhanake antagonist o te oxytocin me te vasopressin V1A, he rite tona hanganga matū ki nga mea e rua, a he nui te hononga mo nga kaiwhiwhi, me te whakataetae ki te oxytocin me te vasopressin V1A kaiwhiwhi, na reira ka aukati i te huarahi mahi o te oxytocin me te vasopressin me te whakaiti te whakaheke uterine.

Tōmua: Teriparatide Acetate API mo te Osteoporosis CAS NO.52232-67-4

Panuku: Carbetocin hei Aukati i te Paheketanga Uterine me te Paheketanga o te Whanau

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