Desmopressin Acetate ki te rongoa i te pokapū mate huka Insipidus
Taipitopito Hua
| Ingoa | Desmopressin |
| nama CAS | 16679-58-6 |
| tātai rāpoi ngota | C46H64N14O12S2 |
| Te taumaha ngota | 1069.22 |
| Tau EINECS | 240-726-7 |
| Te hurihanga motuhake | D25 +85.5 ± 2° (kua tatauhia mo te peptide kore utu) |
| Kiato | 1.56±0.1 g/cm3(Te Matapae) |
| RTECS No. | YW9000000 |
| Nga tikanga rokiroki | Rokiroki ki te 0°C |
| Wairewa | H2O:soluble20mg/mL, mārama, kore tae |
| Te whakarea kawa | (pKa) 9.90±0.15 (Te Matapae) |
Nga kupu taurite
MPR-TYR-PHE-GLN-ASN-CYS-PRO-D-ARG-GLY-NH2; MINIRIN; [DEAMINO1, DARG8] VASOPRESSIN; [DEAMINO-CYS1, D-ARG8]-VASOPRESSIN; DDAVP, TANGATA; DESMOPRESSIN; DESMOPRESSIN, TANGATA; DESAMINO-[D-ARG8] VASOPRESSIN
Tohutohu
(1) Te maimoatanga o te mate huka insipidus pokapū. I muri i te tarukino ka taea te whakaheke i te mimi, te whakaheke i te auau mimi me te whakaiti i te nocturia.
(2) Te maimoatanga o te enuresis i te po (nga turoro 5 tau neke atu ranei).
(3) Whakamatauhia te mahi kukū mimi renal, ka kawe i te tātaritanga rereke o te mahi renal.
(4) Mo te hemophilia me etahi atu mate whakaheke toto, ka taea e tenei hua te whakaiti i te wa whakaheke toto me te aukati i te toto. Ka taea e ia te whakaiti i te nui o te whakaheke toto i roto i te mahi me te oozing postoperative; ina koa me te pehanga toto e tika ana te whakahaere i te wa o te pokanga, ka taea e ia te whakaheke i te toto i roto i te pokanga mai i nga momo tikanga rereke, me te whakaheke i te rere o muri o te mahi, he pai ake te mahi ki te tiaki toto.
Te maimoatanga o te mate huka insipidus
Ko te mate huka insipidus te tuatahi ko te mate o te paopao wai e tohuhia ana e te nui o te whakaputa mimi, te polydipsia, te hypoosmolarity, me te hypernatremia. Ko te ngoikore o te vasopressin (pokapoka mate huka insipidus), te ngoikore ranei o nga whatukuhu o te vasopressin (nephrogenic diabetes insipidus) ka timata. Ma te haumanu, he rite te mate huka insipidus ki te polydipsia tuatahi. He rereke ki te polydipsia tuatahi, ko te pikinga o te inu wai i roto i nga turoro me te mate huka insipidus he whakautu e pa ana ki nga huringa o te pehanga osmotic me te toto toto.
