Terllipressin Acetate mo te toto rereke
Nga kiko o te hua
| Ingoa | N- (N- (N-GlyCyLglycyl) Glycyl) -8-l-lysinevasopressin |
| Ka taea te nama | 14636-12-5 |
| He tātai konukawata | C52h74n16o15s2 |
| Taumaha Momo | 1227.37 |
| Te tau einecs | 238-680-8 |
| Kohua | 1824.0 ± 65.0 ° C (tohua) |
| Tōnu | 1.46 ± 0.1 g / cm3 (tohu) |
| Tikanga rokiroki | Kia mau ki te waahi pouri, te hau hau, te toa i Freezer, i raro -15 ° C. |
| Te nuinga o te waikawa | (PKA) 9.90 ± 0.15 (tohua) |
Hangai
. 1-triglycyl-8-lysinevasopressin; Nα-glycyl-glycyl-glycyl- [8-lysine] -vastoresissin; Nα-glycyl-glycyl-glycyl-lysine-vasopressin; Nα-glycylglycylglycyl-vasopressin; Nα-gly-gly-gly-gly-8-lys-vasopresin; Terllipresin, Terlipressine, Terlipreshina, Terlipressinum.
Whakaaturanga
Terlipresin, ko wai te ingoa matūriki ko te vasopresin vasopresin, he hou te whakarite i te wa roa o te vasopressin roa. He momo o te prodrug, e kore e mahi i a ia ano. He mahi na Aminopeptidase i Vivo ki te "tuku" Ko te Vasopressin kaha i muri i te tango i nga toenga o Glycyl e toru i tana waa. Na reira, ko te Terlipressin te mahi hei reservoir e tuku ana i a Lysine Vasopressin i te reiti pumau.
Ko te hua o te rongoa o terlipressin ko te kirimana i nga uaua maeneene waikore me te whakaheke i te rere toto (penei i te whakaheke toto, me te whakaheke toto. I tetahi atu taha, ka taea hoki te whakaiti i te plasma te hua o te kukume renin, na reira ka piki ake te mahi toto, me te whakapiki i te kaha o te urine ki nga turoro me te mate urui. Ko te Terllipressin anake te raau taero e taea ai te whakapai ake i te oranga o te hunga mate me te rewharewha rereke o te mate pukupuku. I whakamahia te nuinga i roto i te maimoatanga haumanu o te mate hemorrhage. I tua atu, kua pai te whakamahi a Terlipressin i te ate me te whatukuhu. I roto i te katoa, ka whai hua te mahi whai hua ki te whakaohooho whakaohooho me te whakaohooho a Cardiopullotiry. I whakaritea ki te vasopressin, he mea roa tonu, kaore he raru kino, he uaua ki te whakamahi (he pai ake te tiaki me te tino uaua. Te whakaora me te maimoatanga o nga turoro kino.
